Resumen. COLLAZO ALVAREZ, Hiralio; TORRECILLA SILVERIO, Dewar; MORALES FLORAT, Jorge Luis y COLLAZO MARIN, Stephens Yecc. Malignant. CASO CLÍNICO. Malignant oropharyngeal fibrous histiocytoma. Resection and radial reconstruction with fasciocutaneous flap. Histiocitoma fibroso maligno de. LETTERS TO THE EDITOR. Malignant fibrous histiocytoma – a rare hepatic tumor . Histiocitoma fibroso maligno, un tumor hepático raro.

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Any tumor mass over 5 cm is histioocitoma to be a sarcoma. Intraabdominal and retroperitoneal cases may be accompanied by constitutional syndrome, but at other sites it is not a habitual clinical manifestation.

We present a case of a yr-old-man was admitted to our hospital because of abdominal distension causing discomfort, lower extremities edema and weight loss. Haberal I, Samim E. Summary Epidemiology UPS ranks the 4th most common soft tissue sarcoma with a slight male preponderance.

The tumor arises most commonly during the sixth and seventh decades of life. This study supports the results obtained by other authors for MFH in other sites, such as Shinozaki et al.

Histiocitoma fibroso maligno, un tumor hepático raro

The literature on this pathology is reviewed. Most UPS recur locally; distant metastases are common the most frequent is lung. Health care resources for this disease Expert centres Diagnostic tests 4 Patient organisations 32 Orphan drug s No fever, jaundice or maljgno.

Discussion Since the first report of MFH in by O’Brien and Stout, it has been well recognized as the most common malignant soft tissue tumor.

Due to its exceptional location and the implications of this location, we report a new case of malignant fibrous histiocytoma of the soft palate and lateral wall of the oropharynx. Histology of biopsy specimen prior to any treatment is crucial to reach diagnosis and shows pleomorphic spindle cell population with large atypical cells frequently exhibiting numerous irregular mitotic figures, associated regions of hemorrhage and necrosis, associated lymphohistiocytic infiltrate finroso invasion of dermis.


The myxoid variant also exhibits a certain degree of cellular pleomorphism, but much less than the previous subtype. Cochrane Database Syst Rev ;4: Histiocitmoa fibrous histiocytoma MFH represents the most common soft tissue sarcoma in adults. Only 6 cases of malignant fibrous histiocytoma have been reported in the pharynx in the scientific literature.


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Malignant fibrous histiocytoma of the uterus is an extremely rare entity. Radiation-induced malignant fibrous histiocytoma of the neck in a patient with laryngeal carcinoma. Curr Opin Oncol ; Giant malignant fibrous histiocytoma of the uterus. Full text is only aviable in PDF. Kinishi M, Amatsu M.

For that reason, the primary treatment of this type of tumor is resection as extensive as possible. The documents contained in this web site are presented for information purposes only. Si continua navegando, consideramos que acepta su uso. Regional metastases are rare. Primary osseous UPS most commonly occurs in distal femur, proximal tibia, proximal femur and humerus. This neoplasm is defined histopathologically by mesenchymal proliferation of histiocytic cells and fibroblasts with several different growth patterns.

Malignant oropharyngeal fibrous histiocytoma.

Primary malignant fibrous histiocytoma of the mandible: UPS is thought to be derived from a primitive mesenchymal cell capable of differentiating into histiocytes, fibroblasts, myofibroblasts and osteoclasts. Malignant fibrous histiocytoma is recognized as the most malingo soft-tissue sarcoma in adults, although its location in the pharynx is unusual.

The neoplasm was removed surgically with ample resection margins. Subscribe to our Newsletter. Guney E, Yigitbasi OG. No pathological lymph fbiroso enlargement malingo observed. Prog Obstet Ginecol, 46pp. Radial fasciocutaneous flaps produce excellent results in the reconstruction of large defects of the oropharynx, including the palate. This involved resection of the entire soft palate, amygdalar pillars, and the left wall of the oropharynx.


Introduction Malignant fibrous histiocytoma of the uterus is an extremely rare entity.

A meta-analysis published by the SMAC Sarcoma Meta- Analysis Collaboration on the individual data of patients treated with doxorubicin-based chemotherapy schedules is noteworthy regarding this point. J Orthop Sci ;6: En y Gynecol Oncol, 21pp. Disease definition Undifferentiated pleomorphic sarcoma UPS is an aggressive sarcoma of soft tissues or bone that can arise from any part of the body, clinically presenting as swelling, mass, pain, pathological fracture and occasional systemic features and is characterized by high local recurrence and significant metastasis.

Complejo Hospitalario de Ourense. Some immunohistochemical and ultrastructura observations. However, due to the little knowledge we have of it, we are facing histiocitmoa front of an entity malihno very limited diagnostic maligmo therapeutic possibilities. No other masses or evidence of lymphadenopathy were present in the abdomen, pelvis and retroperitoneum.

They were arrayed forming imbricated bundles and adopting a storiform growth pattern in areas, which confirmed the initial diagnosis.

Orphanet: Histiocitoma fibroso maligno

hiwtiocitoma Sometimes amputation may be necessary to remove the whole lesion. Mean diameter was 12,2 cm. To the best of our knowledge less than 35 cases of hepatic MFH have been reported over the last 24 years, since when it was first described 2.