The Chronic Respiratory Disease Questionnaire (CRQ) is the most commonly used disease specific measurement tool to assess HRQL in patients with chronic . Due to their widespread and thorough validation, the following questionnaires are recommended: Chronic Respiratory Disease Questionnaire (CRDQ or CRQ) . To measure health related quality of life in patients with chronic respiratory disease.

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Measuring health related quality of life. Wyrwich et al 29 described the importance of determining the physician’s definition of the MCID in order to better understand and support the use of HRQL measurement tools in the clinic. They also found that the baseline scores for the self-reported test were significantly lower across all domains than for the interviewer-administered questionnaire.

The resulting questionnaire contains 20 items that are believed to represent areas of dysfunction that are most significant to this patient population. Other domains of the CRQ including emotion and mastery significantly correlated with somatisation, anxiety, and depression domains of the SCL Support Center Support Center.

These lower baseline scores and cronic sensitivity of the self-report questionnaire can be attributed to the fact that patients are more likely to report the severity of the impairment when asked to fill out the questionnaire in private, as opposed to questionnxire asked by quuestionnaire interviewer. Guyatt et al 2 found that the CRQ has similar respiraory to the Transitional Dyspnea Index and superior responsiveness to the Rand dyspnea questionnaire, the oxygen cost diagram, and the Rand physical and emotional function questionnaires.

It is recommended that both general and condition specific HRQL questionnaires be administered alongside physiologic tests since each of these contribute unique information regarding disease state and quality of life. The panel’s levels for detecting small, moderate, and large changes were slightly higher than previously determined levels based on patient-perceived change. Although the authors determined that the self-administered version of the CRQ perceives analogous levels of mastery, emotional function, and fatigue, they state that the different versions of the test should not be used interchangeably.


Power of outcome measurements to detect clinically significant changes in pulmonary rehabilitation of patients with COPD. National Center for Biotechnology InformationU.

Outcomes in Cardiopulmonary Physical Therapy: Chronic Respiratory Disease Questionnaire (CRQ)

Rutten-Van Molken et al 3 completed a study to determine the MCID using both methods of between patient comparison and within patient comparison. From these results, the researchers concluded that the CRQ was responsive across all domains for detecting short-term changes.

With the development of the self-administered CRQ, validity of the newer instrument was established by comparing it to the gold standard of the original version. The 3 studies included: A novel, short, and simple questionnaire to measure health-related quality of life in patients with chronic obstructive pulmonary disease. It has high internal consistency and test-retest reliability, as well as moderate to strong construct and convergent validity.

Many studies have examined the correlation between CRQ scores and the physiologic factors believed to contribute to dysfunction in patients with pulmonary disease. A methodological framework for assessing health indices.

Chronic Respiratory Questionnaire (CRQ) | Flintbox

The original CRQ also included a section with individualized questions about dyspnea. Williams et al 26 used standardized response means to assess the sensitivity and also found the CRQ-SR questionnaire be highly sensitive across all domains of the questionnaire indicating that it is able to detect changes following a treatment program.

The following results were reported: The developers found that the CRQ scores at the follow-up assessment were, to a large extent, better than at the initial distribution of the questionnaire, even though spirometry values were only slightly improved.

This degree of test-retest reliability has been shown for both the individualized and standardized forms of the CRQ. The self-administered questionnaire is also reported to have high reliability. Initial testing of reproducibility, responsiveness, and validity was also completed.

Establishing the minimal number of items for a responsive, valid, healthrelated quality of life instrument. Items within the dyspnea domain varied extensively, so the developers of the tool individualized this section, requesting patients to determine the 5 most important activities in their life that are affected by dyspnea. After their second visit, patients from each study were asked to report global ratings of change in questionniare of breath on daily activities, level of fatigue, and emotional status.


Reliability, or reproducibility, can be determined in 3 ways: These changes might be missed if physiological measures are used alone. Recently, clinicians and payers are recognizing that physiological measures do not necessarily relate to function, and functional outcomes need to be measured independently. Patient —assessed auestionnaire outcomes in chronic lung disease: In the clinic, it is not only necessary to measure outcomes of treatment regarding the intervention process, but it is also essential to measure the extent to which the patient feels the treatment has influenced their condition and quality of life.

The CRQ also correlates well with generic measures. All subsequent versions were developed in coordination with the original author, 78 and psychometric properties were evaluated and compared to the original CRQ.

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The expert panel recommended that MCID be associated with a change greater than 2 points in the domain score. Foundations of Clinical Research: However, correlations between the CRQ and other specific measures of pulmonary disease were found to be significantly higher than correlations with generic measures.

Health Q Life Outcomes. In the first assessment, the tool was administered chronid 13 patients all diagnosed with chronic lung disease and the patients were then reassessed 2 to 6 weeks later after treatment had been initiated. Respirxtory determined minimal clinically important differences typically are associated with smaller change scores than physician or expert determined MCIDs, but in general small clinically important changes are associated with score differences of 0.