Monckeberg’s sclerosis is a poorly understood condition associated with . Monckeberg’s sclerosis can coexist with atherosclerotic disease. Carlos Eduardo Barra Couri,1 Geruza Alves da Silva,1 José Antônio Baddini Martinez,1 Mönckeberg’s sclerosis (MS) is a degenerative and apparently .. The current concepts of the pathogenesis of Monckeberg-type arteriosclerosis. Mönckeberg sclerosis (MS) is a calcification of the me- dial layer of . ”Typical morphology of such calcifications in the early stages of the disease is linear de- posits along the . arteries in the absence of atherosclerotic plaque. Mayo Clin.

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Diabetes Care, 17pp. It is intended for rheumatologists, general internists, specialists in related areas, and general practitioners in the country and abroad. The explored arteries were much affected by a process of wall calcification, eliminating any possibility of revascularization. The coexistence of ischaemic heart disease and diabetes—a known risk factor of atherosclerosis, however, raised artetiosclerosis questions about the aetiology of calcification.

Diabetes mellitus and vascular calcification. The frequency of upper limb predominant Monckeberg’s sclerosis is therefore unclear. Some rheumatic conditions, such as polyarteritis aryeriosclerosis and giant cell arteritis may mimic this process.

We report the case of a patient with critical lower limb ischemia without revascularization conditions progressing to limb amputation.

The left lower limb was painless, hyperemic, with normal femoral pulse and absence of popliteal and distal pulses. In other projects Wikimedia Arteriosclerosks. Atherosclerosis has the following main risk factors: Bone scintigram shows increased uptake of 99 m Tc-methylene diphosphate in the calcified femoral arteries and on the anterior surface of the neck.

The present report provides a new insight about this disease, i.

Monckeberg’s arteriosclerosis as a cause of lower limb critical ischemia: case report

Hypertension Hypertensive heart disease Hypertensive emergency Hypertensive nephropathy Essential hypertension Secondary hypertension Renovascular hypertension Benign hypertension Pulmonary hypertension Systolic hypertension White coat hypertension.

Translumbar aortography shows near-total obstruction of the femoral arteries. This association is further supported by the increased incidence of vascular calcification following lumbar sympathectomy.


Ueber die reine Mediaverkalkung der Extremitaetenarterien und ihr Verhalten zur Arteriosklerose.

A transesophageal echocardiogram was carried out, which reported segmental contractility disorders and valve leaflets without the presence of vegetations, but with multiple atheromatous plaques in the entire aortic trajectory. After repeated failures at negotiating a hydrophilic wire after successful sheath insertion; fluoroscopy revealed extensive calcification of radial and ulnar arteries extending up to the brachial artery.

Media calcification and intima calcification are distinct entities in chronic kidney disease. Coronary calcification in patients with chronic kidney disease and coronary artery disease. Arteriovenous fistula Arteriovenous malformation Telangiectasia Hereditary hemorrhagic telangiectasia. Continuing navigation will be considered as acceptance of this use. Typically calcification is observed in the arteries of the upper and lower limb although it has been seen in numerous other medium size arteries.

Int J Oral Maxillofac Surg, 44pp. All peripheral pulses were palpable; arterial wall thickening was noted in both radial arteries. A neck X-ray and computed tomography evidenced grossly calcified areas of soft tissue in the topography of the pharynx and larynx.

arteriozclerosis Okuno Y, Sato K. It is here where becomes important a large list of etiologies that can simulate their clinical characteristics at the time of making differential diagnosis, since their treatment and prognosis will depend on it.

Further studies are needed for a better understanding of this disease, as well as to improve its diagnosis and treatment. Investigations Routine laboratory tests including blood glucose, renal serum creatinine 1.

Anatomopathological test of the amputated limb arterioscledosis ischemic necrosis, atherosclerosis with fibrous plaques and calcification of the medial layer in the femoral, popliteal and tibial arteries. However, the risk arterioscleosis triggering even more tissue calcification secondary to tissue damages discouraged the realization of this procedure. Recent studies, however, have demonstrated that MS is a risk factor for cardiovascular disease and peripheral artery obstruction [ 145 ].

Monckeberg’s sclerosis is a poorly understood condition associated with generalised atherosclerosis and chronic kidney disease. Frankini II ; Aline S.

Incidentally detected Monckeberg’s sclerosis in a diabetic with coronary artery disease

So, with the aim of monckeerg further vascular and soft tissue calcification, intravenous dissodic pamidronate was administred 60 mg IV diluted in mL of saline solution once a day for 1 day. This calcification is usually circumferential and may affect the vessel either focally or diffusely. There were also no symptoms suggestive of peripheral arterial insufficiency including paraesthesias and non-healing ulcers in the extremities.


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This article has been cited by other articles in PMC. Connective tissue and its heritable disorders: The authors thank the Department of Pathology of Sikkim Manipal Institute of Medical Sciences for extending them all the necessary help regarding the histopathologic report and the picture, as well as the OBG staff for their support. The result is progressive stiffening monckberg the elastic layer of the arterial wall.

Calcium deposits form in the middle layer of the walls of medium-sized vessels, and these vessels become calcified independently of atherosclerosis. Medical management with statin and antiplatelets was also initiated. Although one can argue about the possible role of upper airway obstruction in intensifying the local deposition of calcium in the mnockeberg tissue of the pharynx, the diagnosis of MS was well documented in this case.

The femoral arteries appeared to be thickened and pulses were frail although there were no signs of acute limb ischemia. A year-old Brazilian woman was referred to the hospital with a year history of an increasing size of the anterior portion of the neck associated with progressive exertional dyspnea, nighttime snoring and coughing, dysphagia of solids and daytime sleepiness.

Her general condition was good. Obesity, age, male sex, positive family history and alcohol consumption are well known as major risk factors for this disorder in adults. Epidermodysplasia verruciformis associated with idiopathic