El Angiofibroma nasofaríngeo juvenil es un tumor benigno vascular (pero que tardíamente Se localiza en la pared posterolateral de la grita nasal a nivel del vínculo de la apófisis esfenoidal del hueso palatino. Esta localización conforma el. Nasal cavity, paranasal sinuses, nasopharynx – Nasopharyngeal angiofibroma. Juvenile nasopharyngeal angiofibroma (JNA) is a rare and benign but locally in the nasopharynx and nasal cavity, leading to manifestations such as nasal.

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Invading the pterygopalatine fossa or the maxillary, ethmoid, or sphenoid sinus with bone destruction.

Disease definition Juvenile nasopharyngeal angiofibroma JNA is a rare and benign but locally aggressive fibrovascular tumor arising from the posterolateral wall of the nasopharynx, which affects mainly young and adolescent males onset usually occurring between years of age and that presents as a mass in the nasopharynx and nasal cavity, leading to manifestations such as nasal obstruction, epistaxis, profound facial swelling, proptosis or diplopia.

Full occupation of the pterygomaxillary fossa, anterior displacement nazal the posterior wall of the maxillary antrum. Patients requiring craniotomy for neurosurgical access were excluded from the sample, since the findings associated with this route angiofiboma outside the scope of the present study.

The patient with oculomotor nerve palsy had no improvement at the month follow-up.

Retrieved 29 June Several reports suggest that JNA regresses over time. Surgical approaches for conventional techniques include transpalatal, transmaxillary, lateral rhinotomy, mid-facial degloving, extended sublabial Denker, and Le Fort type I osteotomy 11,13,20, The combination of different accesses to the tumor can be required 9. Conclusion Operative treatment of nasopharyngeal angiofibroma with intracranial extension is one of the major challenges of ENT and neurosurgical practice.


None of our patients angifibroma complications due to embolization. Invading the angioribroma fossa or orbital region without intracranial involvement. This feature may be helpful is differentiating from other more aggressive lesions.

IIIb Erosion of the skull base with extensive intracranial extension with or without cavernous sinus invasion. Bony erosion of the nasal cavity, hard palate and angioifbroma plates is also common.

Angiofibroma nasofaríngeo juvenil

Changes in staging and treatment. The third patient with a Fisch I tumor underwent surgery with embolization, but without clamping of the external carotid arteries. The 3 patients who underwent combined surgeries experienced intraoperative bleeding, requiring nasal packing and replacement of blood products during surgery. Int J Pediatr Otorhinolaryngol.

Extended osteoplastic maxillotomy for total excision of giant multicompartmental juvenile nasopharyngeal angiofibroma. Longer duration of surgery is associated with greater changes in body homeostasis due to surgical trauma.

Olfactory neuroblastoma Olfactory neuroblastoma.

Thus, early diagnosis, accurate staging and adequate treatment are essential in the management of this lesion. InFriedberg called it juvenile angiofibroma. This may be attributed to a rich vasculature and lack of encapsulation.

The recurrence rate of endoscopically resected tumors has been shown to be low, and we found that none of our 20 patients experienced tumor recurrence. Figure 7 shows mast cells in toluidine blue stain.


Pathology Outlines – Nasopharyngeal angiofibroma

Open in a separate window. Arch Otolaryngol Head Neck Surg. This page was last edited on 29 Septemberat Moreover, the mean blood loss in these patients was mL. Impaired Eustachian tube function, facial deformity, proptosis and changes in visual acuity may be seen. Case 7 Case 7. Publicado por Elsevier Editora Ltda. Synonyms or Alternate Spellings: In this study, we have described our experience in treating 20 patients with naasl angiofibromas in the Department of Otorhinolaryngology.

Juvenile nasopharyngeal angiofibroma

About Blog Go ad-free. Fisch classification, however, is currently accepted. Continuous growth involves the sphenoidal sinus, nasal fossa and middle turbinate, pterygomaxillary fossa and the posterior wall of the maxillary sinus as seen in the present case.

Case 3 Case 3. Efforts to determine the pathogenesis of the tumor have been done by studying the expression of various growth factors and oncogenes such as C-KIT and C-MYC. The demographic angiofibgoma, surgical techniques used, immediate and delayed complications, and recurrence rate of the sample are listed in Table 1.

These classifications are very important in helping surgeons decide the appropriate surgical approach. They may be locally aggressive. The other ajgiofibroma patients required only endoscopic surgery. Int J Pediatr Otorhinolaryngol.