Espasmo coronario secuencial en angina variante de Prinzmetal con Sequential Coronary Spasm in Prinzmetal’s Angina Presenting as Syncope. Full text -. denominação de A variant form of angina pecto- ris(1, 2). Este tipo de angina de peito é designado por angina variante de Prinzmetal ou mais sim- plesmente. PRINZMETAL’S ANGINA DURING EXTRADURAL ANAESTHESIA FlO. 6. . LA VARIANTE PRINZMETAL DE ANGINA, DURANTE ANESTESIA.

Author: Shagrel Vozilkree
Country: Djibouti
Language: English (Spanish)
Genre: Medical
Published (Last): 20 March 2011
Pages: 336
PDF File Size: 13.11 Mb
ePub File Size: 9.73 Mb
ISBN: 130-3-44706-291-4
Downloads: 66690
Price: Free* [*Free Regsitration Required]
Uploader: Zulmaran

Variange infective endocarditis Subacute bacterial endocarditis non-infective endocarditis Libman—Sacks endocarditis Nonbacterial thrombotic endocarditis. During these “hot phases”, stimuli that would not usually provoke an episode of variant angina, may induce an episode.

However, individuals commonly develop tolerancei. Varians anginaVasospastikus anginaPrinzmetal-angina. ECG changes compatible but not indicative of variant angina include elevations rather than depressions of the ST segment or an elevated ST segment plus a widening of the R wave to create a single, broad QRS complex peak termed the “monophasic curve”.

Myron Prinzmetal described a type of angina that differed from the classic cases of Heberden angina in that it commonly occurred in the absence of exercise or exertion. Fluctuation of spastic location in patients with vasospastic angina: Accelerated idioventricular rhythm Prinzmetsl polymorphic Torsades de pointes.

Also in contrast to atherosclerotic disease, the condition appears to be more prinzmmetal amongst the Japanese as compared with Caucasians 2.

Prevention of vasospasm Complications Resources References Extra: Definition NCI A variant prinzzmetal of angina pectoris caused by coronary artery vasospasm, usually occurring spontaneously and frequently associated with ST segment elevation. Exercise ECG stress testing is typically negative but during the hot phase, exercise-induced spasm may occur in half of the variant angina patients 4.

Consequently, provocative spasm testing has been developed to aid in its diagnosis. Prinzmetal’s angina or coronary artery vasospasm. Retrieved April 28, Background InWilliam Heberden, a British physician, aptly described the features of classical angina of effort, remarking on its occurrence with exertion and prompt resolution with rest.

Variantf Pectoris, Variant C A variant of the variant.


A variant form of angina pectoris”. D bradycardia Sick sinus syndrome Heart block: Other factors thought to be associated with the development of variant angina include: Variant angina of Prinzmetal with normal coronary arteriograms.

Medicines can help control the spasms. Individuals with variant angina my have many undocumented episodes of symptom-free coronary artery spasm that are associated with poor blood flow to portions of the heart and subsequent irregular and potentially serious heart arrhythmias.

Variant Angina

All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License. Accordingly, individuals with variant angina should be intermittently evaluated for this using long-term ambulatory cardiac monitoring. One strategy to avoid this development is to schedule nitroglycerin-free periods of between 12 to 14 hours between doses of long-acting nitroglycerin formulations. Long-term prognosis of “variant” angina with medical treatment.

Harrison’s principles of internal medicine. Search Bing for all related images.

Variant angina

Journal of Cardiovascular Pharmacology and Therapeutics. Despite the availability of effective therapies for coronary artery spasm, the diagnosis of variant angina is infrequently considered in patients with angina. These attacks can be very painful. A variant form of angina pectoris caused by coronary artery vasospasm, usually occurring spontaneously and frequently associated prinzmetla ST segment elevation.

And, they should avoid any of the recreational and therapeutic drugs listed in the above Signs and symptoms sects as well as blockers of beta receptorssuch as propranololwhich, theoretically, may worsen vasospasm by inhibiting Beta-2 adrenergic receptor vasodilation mediated by these receptors naturally occurring stimulator, epinephrine. Track your angina symptoms with our Angina Log. Current Understanding and the Role of Inflammation”.

Prinzmetal’s or Prinzmetal Angina, Variant Angina and Angina Inversa | American Heart Association

Patients should address specific medical concerns with their physicians. The potassium channel opener, nicorandil, and the rho kinase inhibitor, ed, have both been shown to be effective in preventing coronary spasm episodes and are useful therapies for this condition. Circadian variation of exercise capacity in patients with Prinzmetal’s variant angina: Patients complaining of chest pain should be immediately checked for an abnormal electrocardiogram ECG.

In all of these emergency cases, percutaneous coronary intervention to stent areas where coronary arteries evidence spasm is only useful in individuals who have concomitant coronary atherosclerosis on coronary angiogram. Considering these differences, Prinzmetal coined the term “variant angina” and speculated that the condition was due to an “increased coronary tonus” or vasospasm. To reduce the burden of cardiovascular disease. Whereas exercise does not typically precipitate an episode of variant angina, hyperventilation and exposure to the cold can provoke episodes.


Cardiac examination of individuals with variant angina is usually normal in the absence of current symptoms.

The disorder seems to occur more often in women than men, has a particularly high incidence in Japanese males as well as females, and afflicts individuals who may smoke tobacco products but exhibit few other cardiovascular risk factors. The temporal pattern of the rest angina warrants close consideration in evaluating these patients, both in relation to its waxing and waning nature and its distinct circadian rhythm. Intravascular ultrasound detection of atherosclerosis variantd the site of focal vasospasm in angiographically normal or minimally narrowed coronary segments.

Prinzmetal’s angina is a chronic condition that will need to be followed by your healthcare provider even though the prognosis is generally good. Ambulatory ECG monitoring may be useful, particularly during a hot phase of the condition, for detecting episodes of ST segment changes as well as associated arrhythmias.

The diagnosis must also be considered prinnzmetal patients with recurrent rest angina associated with syncope or even cardiac arrest, since prinzmstal with variant angina may experience malignant arrhythmias during their ischaemic episodes.

Myocarditis Chagas disease Cardiomyopathy Dilated Alcoholic Hypertrophic Restrictive Loeffler endocarditis Cardiac amyloidosis Endocardial fibroelastosis Arrhythmogenic right ventricular variamte.

For a portion of patients, variant angina may be a manifestation of a more generalized episodic smooth muscle -contractile disorder such as migraineRaynaud’s phenomenonor aspirin-induced asthma.