Follicular mucinosis is a term that encompasses three related entities. Alopecia mucinosa, Urticaria-like follicular mucinosis, and cutaneous lymphoma related. On hair-bearing skin (e.g. scalp), overlying alopecia is notable, hence the term “ alopecia mucinosa” (see Figure 5). Plaques are often composed of densely. Alopecia mucinosa is a skin disorder that generally presents, but not exclusively, as erythematous plaques or flat patches without hair primarily on the scalp.

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However, monoclonality does not distinguish lymphoma-associated FM from idiopathic FM. Immunohistochemistry showed the infiltrating lymphocytes to be CD3 and CD4 positive.

With loss of the follicle, alopecia may be evident clinically.

The upper and mid dermis had a moderately dense perivascular lymphocytic infiltrate with few eosinophils. Mycosis fungoides associated follicular mucinosis on posterior scalp.

Clonal FM may regress completely. Rajiv Joshi and Vinay Gopalani 1. Few of the follicular infundibula showed features of follicular mucinosis with mild spongiosis, separation of the keratinocytes from one another, and clear spaces between the keratinocytes, which contained wisps of light blue-gray mucin.

Retrieved mucinosz ” https: Isotretinoin is pregnancy category X. From Wikipedia, the free encyclopedia. Controversy exists as to whether the disease is a neoplastic process or a reactive process. Alopecia mucinosa most commonly affects face, neck and scalp, but any part of the body may be affected. Some papers[ 411 ] have shown good response of follicular mucinosis to minocycline, however, contrary results with very minimal or no improvement has also been reported in patients with Alopecia mucinosa who were treated with minocycline for more than 3 months.

The biopsy showed a moderately dense superficial and mid perivascular infiltrate of lymphocytes with occasional eosinophils without any granulomas in the sections.


In sum, we present three cases of Alopecia mucinosa, who presented with single lesions on the face, had follicular mucinosis on biopsy and who healed rapidly and completely with initiation of antileprosy treatment.

Discussion The objective of this paper is to draw attention to an unusual finding, that is, rapid and complete response of Alopecia mucinosa to antileprosy treatment with no subsequent relapse over fairly long periods of posttreatment observation.

A year-old girl presented in Marchwith hair loss over left eyebrow and dry hypopigmented skin of adjacent forehead. Rajiv Joshi Department of Dermatology, P. The treatment was, however, mucinos a month later as she was in her village for the summer holidays. Mucins look like stringy clear mucinnosa whitish goo mainly composed of hyaluronic acid, a normal component of the ground substance surrounding collagen in the dermis. Vanessa Ngan, Staff Writer, Inflammatory plaques with alopecia characterized by root sheath mucinosis.

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Department of Dermatology, P. Andrews’ Diseases of the Skin: Nil Conflict of Interest: By registering you consent to the collection and use of your information to provide the products and services you have requested from us and as described in our privacy policy and terms and conditions. Disorders of skin appendages L60—L75— Superficial and deep, perivascular and perifollicular, infiltrate of lymphocytes and numerous eosinophils. Follicular infundibulum keratinocytes and outer root sheath are separated by pools of mucin Mixed infiltrate of lymphocytes, histiocytes and conspicuous eosinophils Marked follicular dilation with cyst formation and perifollicular scarring Both the mucinpsa and and affected epithelium are typically infiltrated by lymphocytes, histiocytes and eosinophils In cases associated with lymphoma, mucinosz lymphocytes, convoluted lymphocytes, large transformed mucinoxa and mitotic figures may be seen.


Koilonychia Nail clubbing behavior: Several other forms of mucinosis are described and classified. Lesions are often asymptomatic but may itch or burn; they develop over weeks or months not days.

Alopecia mucinosa | DermNet NZ

Response within 3 months; recurrence may occur upon discontinuation. Alopecia areata totalis universalis Ophiasis Androgenic alopecia male-pattern baldness Hypotrichosis Telogen effluvium Traction alopecia Lichen planopilaris Trichorrhexis nodosa Alopecia neoplastica Anagen effluvium Alopecia mucinosa cicatricial alopecia: DermNet NZ does not provide qlopecia online consultation service.

Dose, frequency, and duration of therapy is indicated where available and is based on published literature. Lymphocytes were seen infiltrating the follicular epithelium but no atypical lymphocytes were seen. A year-old boy presented in Septemberwith a hypopigmented and hypoaesthetic shiny patch on the left cheek of few months duration.

Views Read Edit View history. In this article we describe three cases, two children with a single facial lesion clinically suspected to be leprosy in whom biopsy showed follicular mucinosis without granulomas. Mucosal surfaces, genitalia, and acral palms and soles areas are usually spared. If you have any concerns with your skin or its treatment, see a alopevia for advice.

Alopecia mucinosa

Click here for information on linking to our website or using our content or images. Alopecix here for patient related inquiries. Intralesional corticosteroids or excision should be considered for refractory or localized lesions, where cosmetically acceptable.

Single lesion Alopecia mucinosa in children and young adults responds rapidly and completely with antileprosy treatment. Plaques are often composed of densely aggregated individual papules, many of which have a central spine.