ALMOTRIPTAN MALATE PDF

In addition, it is expected that almotriptan malate (AXERT®) is generally Trial to Evaluate the Efficacy of Almotriptan Malate (AXERT®) Milligram. Almotriptan is a headache medicine that narrows blood vessels around the brain. Almotriptan also reduces substances in the body that can. Almotriptan is a triptan drug for the treatment of migraine headaches. Almotriptan Malate, Tablet, coated, mg/1, Oral, Patriot Pharmaceuticals,

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Dofetilide The metabolism of Dofetilide can be decreased when combined with Almotriptan. Flavoxate Almotriptan may decrease zlmotriptan excretion rate of Flavoxate which could result in a higher serum level. MAO-A is responsible for the formation of the indoleacetic acid metabolite, whereas cytochrome P CYP3A4 and CYP2D6 catalyzes the hydroxylation of the pyrrolidine ring to an intermediate that is further oxidized by aldehyde dehydrogenase to the gamma-amino-butyric acid derivative; both metabolites are inactive.

Axert (almotriptan malate) dose, indications, adverse effects, interactions from

Additive effects malzte occur, and the risk of serotonin syndrome may be increased. Dibenzepin The risk or severity of serotonin syndrome can be increased when Almotriptan is combined with Dibenzepin. Entacapone The risk or severity of adverse effects can be increased when Entacapone is combined with Almotriptan.

If almotriptan dose adjustments are made, re-adjust the dose upon completion of telaprevir treatment. Patients with severe renal impairment require dosage reduction.

Eslicarbazepine The risk or severity of adverse effects can be increased when Almotriptan is combined with Eslicarbazepine. Fluprednisolone The metabolism of Fluprednisolone can be decreased when combined with Almotriptan. It alotriptan the blood vessels constriction in the brainstem. Epoprostenol Almotriptan may decrease the excretion rate of Epoprostenol which could result in a higher serum level.

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Disopyramide Disopyramide may decrease the excretion rate of Almotriptan which could result in a malaye serum maalte. It is intended to reduce acute migraine symptoms, as it will only treat a migraine that has already begun.

Epirizole Epirizole may decrease the excretion rate of Almotriptan which could result in a higher serum level. Additionally, ergot alkaloids are serotonergic agents whose effects on serotonin may be additive to those of the serotonin-receptor agonists. Cyclobenzaprine The metabolism of Cyclobenzaprine can be decreased when combined with Almotriptan.

The mean elimination half-life of almotriptan is 3 to 4 hours. Almotriptan is partially metabolized by the hepatic isoenzyme CYP3A4; telaprevir inhibits this isoenzyme. Fosfomycin Fosfomycin may decrease the excretion rate of Almotriptan which could result in a higher serum level.

Almotriptan – DrugBank

Botulinum toxin type A The risk or severity of adverse effects can be increased when Botulinum Toxin Type A is combined with Almotriptan. Antrafenine Antrafenine may decrease the excretion rate maalte Almotriptan which could result in a higher serum level.

Gentamicin Gentamicin may decrease the excretion rate of Almotriptan which could result in a higher serum level. Hydrocortisone aceponate The metabolism of Almotriptan can be increased when combined with Hydrocortisone aceponate. Delavirdine The metabolism of Almotriptan can be decreased when combined with Delavirdine.

Moderate Administering almotriptan with elbasvir; grazoprevir may result in elevated almotriptan plasma concentrations.

Adalimumab Zlmotriptan metabolism of Almotriptan can be increased when combined with Adalimumab. Eltrombopag The metabolism of Almotriptan can be decreased when combined with Eltrombopag. Atropine The risk or severity of hypertension can be increased when Atropine is combined with Almotriptan.

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Dabrafenib The metabolism of Almotriptan can be decreased when combined with Dabrafenib.

Axert® (almotriptan malate)

Cyclopropane The risk or severity of adverse effects can be increased when Almotriptan is combined with Cyclopropane. Although adverse retinal effects were not observed during a toxicity study in animals, in theory, toxicity to melanin-rich tissue, such as the eye, may occur during chronic use of the drug.

Belinostat The metabolism of Almotriptan can be decreased when combined with Belinostat.

Vilazodone and the serotonin-receptor agonist should be discontinued if serotonin syndrome occurs and supportive symptomatic treatment should be initiated. During a week toxicity study in animals, slight corneal opacities developed in 3 of 14 almotriptan-treated animals. Patients who experience signs or symptoms suggestive of decreased arterial flow, such as Raynaud’s phenomenon or ischemic bowel syndrome, after the use of almotriptan should be further evaluated.

Amphetamine The risk or severity of serotonin syndrome can be increased when Amphetamine is combined with Almotriptan. Amoxapine rarely causes serotonin syndrome when used alone, but the risk may be increased when combined with other serotonergic agents.

Dihydroergocryptine Dihydroergocryptine may increase the vasoconstricting activities of Almotriptan. Benzthiazide Benzthiazide may increase the excretion rate of Almotriptan which could result in a lower serum level and potentially a reduction in efficacy. It is not known whether selective monoamine oxidase B inhibitors e.